Ploidy studies in adenomatous polyps of colon.

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Ploidy studies in adenomatous polyps of the colon.

The nuclei of colonic adenomatous polyps and some colonic carcinomas have a normal diploid profile. The remaining carcinomas are aneuploid, and this change most probably occurs after the dysplasia that determines invasiveness, because even adenomatous polyps with carcinoma in situ are diploid.

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Correlation of nuclear ploidy with histology in adenomatous polyps of colon.

Histological sections of adenomatous polyps of the colon showing carcinoma were studied by video image analysis. Nuclear DNA content and morphology were measured in regions identified as either dysplasia, carcinoma confined to the mucosa, or carcinoma invading the muscularis mucosa. Where carcinoma was present, areas of dysplasia in the same polyp were found to have similar distributions of nuc...

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Association of Helicobacter pylori Infection With Colon Cancer and Adenomatous Polyps

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ژورنال

عنوان ژورنال: Journal of Clinical Pathology

سال: 1986

ISSN: 0021-9746

DOI: 10.1136/jcp.39.11.1276-a